brochure sur les inhibiteurs, agonistes et bibliothèques de criblage de MedChemExpress
brochure couvrant des produits inhibiteurs, agonistes et bibliothèques de criblage par MCE
Contenu du document
www.MedChemExpress.com
MedChemExpress
Inhibitors & Agonists
- 25,000+ specific inhibitors & agonists targeting 20+ classic signaling pathways
Compound Screening Libraries
- 50+ compound screening libraries optimized for disease mechanism revealing & drug repurposing
Publications citant l'utilisation des produits de MCE
- Nature. 2020 Apr;580(7803):386-390.
- Cell. 2020 Apr 6. pii: S0092-8674(20)30268-3.
- Cell. 2020 Mar 5;180(5):941-955.e20.
- Nature. 2020 Mar;579(7799):433-437.
- Science. 2020 Feb 14;367(6479):806-810.
- Cell. 2020 Feb 20;180(4):645-654.e13.
- Nature. 2019 Dec;576(7786):274-280.
- Cell. 2019 Dec 12;179(7):1483-1498.e22.
- Cell. 2019 Dec 12;179(7):1566-1581.e16.
- Nature. 2019 Nov;575(7782):375-379.
- Nature. 2019 Nov;575(7784):683-687.
- Nature. 2019 Oct;574(7777):264-267.
- Cell. 2019 Oct 31;179(4):864-879.e19.
- Nat Nanotechnol. 2019 Oct;14(10):988-993.
- Nat Biotechnol. 2019 Oct;37(10):1209-1216.
- Cell. 2019 Aug 22;178(5):1145-1158.e20.
- Cell. 2019 Aug 22;178(5):1132-1144.e10.
- Nature. 2019 Jul;571(7763):127-131.
- Science. 2019 Jul 19;365(6450).
- Cell. 2019 Jul 25;178(3):585-599.e15.
- Cell. 2019 Jul 11;178(2):330-345.e22.
Inhibitors & Agonists
We offer over 25,000 selective inhibitors and agonists targeting 375 key proteins in 20+ signaling pathways. Our products have applications in different disease areas and consist of high-grade products only.
Screening Libraries
MCE compound screening libraries consist of over 10,000 small molecules with validated biological and pharmacological activities.
Quality
Our robust quality control methods assure product high quality and purity.
Experience
We track the latest scientific innovations and provide you access to the newest compounds.
Validation
Our products' biological activities are validated by worldwide customers and published in top scientific journals such as Nature, Science, and Cell.
Partner
We work together with renowned research institutes and pharmaceutical companies.
www.MedChemExpress.com
Inhibitors • Agonists • Screening Libraries
Signaling Pathways
- PI3K/Akt/mTOR
- Epigenetics
- Autophagy
- Apoptosis
- Cell Cycle/DNA Damage
- Metabolic Enzyme/Protease
- Protein Tyrosine Kinase/RTK
- Immunology/Inflammation
- Stem Cell/Wnt
- Anti-infection
- JAK/STAT Signaling
- MAPK/ERK Pathway
- GPCR/G Protein
- Neuronal Signaling
- Membrane Transporter/Ion Channel
- Cytoskeleton
- NF-?B
- TGF-beta/Smad
- VD/VDR
- Antibody-drug Conjugate/ADC Related
- PROTAC
Compound Screening Libraries
Our ready-to-use MedChemExpress (MCE) compound libraries consist of over 10,000 small molecules with validated biological and pharmacological activities. They are available for high-throughput screening (HTS) and high-content screening (HCS). Compound libraries are useful professional tools for drug discovery and new indication research. Safety and effectiveness have been confirmed by literature, patent reports, and clinical research. Many products are FDA-approved.
Virtual Screening
Virtual screening is a computational technique used to search libraries of small molecules to identify those structures most likely to bind to a drug target. It has become a crucial step in early-stage drug discovery, offering a fast tool for drug design with ligand-based and structure-based virtual screening, a super high-performance computer, a professional molecular simulation team, and competitive pricing.
Dye Reagents
Dye reagents are a class of aromatic hydrocarbons and heterocyclic compounds that can be excited through photoexcitation-fluorescence groups and emit fluorescence. Applications include immunofluorescence, fluorescent probes, cell staining, ion indicators, and specific DNA staining for chromosome analysis, cell cycle, apoptosis, and other related research. They offer advantages such as high sensitivity, high selectivity, cost-effectiveness, and strong technical support.
