plaquette sur les inhibiteurs, agonistes et bibliothèques de criblage de MedChemExpress
présentation des produits et services de MedChemExpress
Contenu du document
MedChemExpress
www.MedChemExpress.com
Inhibitors & Agonists
25,000+ specific inhibitors & agonists targeting 20+ classic signaling pathways.
Compound Screening Libraries
50+ compound screening libraries optimized for disease mechanism revealing & drug repurposing.
Publications Citing Use of MCE Products
- Nature. 2020 Apr;580(7803):386-390.
- Cell. 2020 Apr 6. pii: S0092-8674(20)30268-3.
- Cell. 2020 Mar 5;180(5):941-955.e20.
- Nature. 2020 Mar;579(7799):433-437.
- Science. 2020 Feb 14;367(6479):806-810.
- Cell. 2020 Feb 20;180(4):645-654.e13.
- Nature. 2019 Dec;576(7786):274-280.
- Cell. 2019 Dec 12;179(7):1483-1498.e22.
- Cell. 2019 Dec 12;179(7):1566-1581.e16.
- Nature. 2019 Nov;575(7782):375-379.
- Nature. 2019 Nov;575(7784):683-687.
- Nature. 2019 Oct;574(7777):264-267.
- Cell. 2019 Oct 31;179(4):864-879.e19.
- Nat Nanotechnol. 2019 Oct;14(10):988-993.
- Nat Biotechnol. 2019 Oct;37(10):1209-1216.
- Cell. 2019 Aug 22;178(5):1145-1158.e20.
- Cell. 2019 Aug 22;178(5):1132-1144.e10.
- Nature. 2019 Jul;571(7763):127-131.
- Science. 2019 Jul 19;365(6450).
- Cell. 2019 Jul 25;178(3):585-599.e15.
- Cell. 2019 Jul 11;178(2):330-345.e22.
Inhibitors & Agonists
We offer 25,000+ selective inhibitors and agonists targeting 375 key proteins in 20+ signaling pathways, with applications in different disease areas.
Screening Libraries
MCE compound screening libraries consist of 10,000+ small molecules with validated biological and pharmacological activities.
Quality
Our robust quality control methods assure product high quality and purity.
Experience
We track the latest scientific innovations and provide you access to the newest compounds.
Validation
Our products' biological activities are validated by worldwide customers and published in top scientific journals.
Partner
We work together with renowned research institutes and pharmaceutical companies.
Table of Contents
- Signaling Pathways
- PI3K/Akt/mTOR
- Epigenetics
- Autophagy
- Apoptosis
- Cell Cycle/DNA Damage
- Metabolic Enzyme/Protease
- Protein Tyrosine Kinase/RTK
- Immunology/Inflammation
- Stem Cell/Wnt
- Anti-infection
- JAK/STAT Signaling
- MAPK/ERK Pathway
- GPCR/G Protein
- Neuronal Signaling
- Membrane Transporter/Ion Channel
- Cytoskeleton
- NF-?B
- TGF-beta/Smad
- VD/VDR
- Antibody-drug Conjugate/ADC Related
- PROTAC
Compound Screening Libraries
The libraries are used for high-throughput screening (HTS) and high-content screening (HCS). Compound libraries are professional tools for drug discovery and new indication research.
MCE Bioactive Screening Libraries
- HY-L001: Bioactive Compound Library
- HY-L001P: Bioactive Compound Library Plus
- Clinical and Approved Drugs
- HY-L035: Drug Repurposing Compound Library
- HY-L035P: Drug Repurposing Compound Library Plus
- HY-L066: FDA Approved & Pharmacopeial Drug Library
Virtual Screening
Virtual screening is a computational technique used to search libraries of small molecules to identify those structures most likely to bind to a drug target.
Common Libraries
- MCE Bioactive Compound Library: 10,000+ bioactive and structurally diverse compounds.
- MCE Fragment Library: 8,000+ high-quality molecules for fragment-based drug discovery (FBDD).
- HTS Compound Library: 2,141,514 diverse screening compounds.
Dye Reagents
Dye reagents are aromatic hydrocarbons and heterocyclic compounds that can emit fluorescence. Applications include immunofluorescence, fluorescent probes, cell staining, ion indicators, and specific DNA staining for chromosome analysis.
For research use only. We do not sell to patients.
